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本文报道于1987～1989年对6例急性白血病患儿强化疗后的骨髓象进行了动态观察,结果表明,部分病例可以出现较长时间的骨髓造血功能不全,其持续时间可长达5～6周,甚至更长。此时粒系原始细胞比例增高>5%,最高可达21.2%,但随着休疗期的适当延长,粒细胞成熟障碍消失,原始细胞自然下降<5%,红系、巨核系增生正常。提示此种情况系因化疗后骨髓造血功能不全,而非复发或未缓解。
This article reports from 1987 to 1989 in 6 cases of acute leukemia in children with bone marrow after intensive chemotherapy showed that the dynamic results showed that in some cases there may be a longer period of bone marrow hematopoietic failure, the duration of up to 5 to 6 Week, even longer. At this time, the proportion of granulocyte blast cells increased by> 5%, up to 21.2%. However, with the proper extension of rest period, the maturation of granulocytes disappeared, and the number of primordial cells decreased by 5%. The erythroid and megakaryocyte proliferated normally. Tip of this situation is due to bone marrow hematopoietic dysfunction after chemotherapy, rather than relapse or not relief.