论文部分内容阅读
目的:探讨急性有机磷农药中毒时输血治疗对血清胆碱酯酶活力的影响以及对于阿托品用药时间的影响。方法:对54例入院时血清胆碱酯酶活力<2 000KU/L(正常值4 000~11 000KU/L)的有机磷农药中毒患者进行回顾分析,其中给予输血治疗组34例,未输血组20例。分别统计输血组及未输血组患者血清胆碱酯酶活力恢复至2 800KU/L(正常值70%)以及3 600KU/L(正常值90%)以上的时间,并统计两组患者脱离阿托品的时间。结果:输血组在血清胆碱酯酶活力恢复至2 800KU/L以及3 600KU/L以上所需的时间均小于未输血组,差异有统计学意义(P<0.01),两组患者脱离阿托品所需的时间差异无统计学意义(P>0.05)。结论:急性有机磷农药中毒时输血治疗能显著提高血清胆碱酯酶活力恢复速度,但对脱离阿托品的时间无明显影响,即对疾病病程无明显影响。
Objective: To investigate the effects of transfusion therapy on serum cholinesterase activity and the time of atropine administration in acute organophosphorus pesticide poisoning. Methods: 54 cases of organophosphorus pesticide poisoning in patients with serum cholinesterase <2 000KU / L (normal value 4 000 ~ 11 000KU / L) were retrospectively analyzed. Among them, 34 cases were given blood transfusions, 20 cases. Serum cholinesterase activity was recovered to 2 800KU / L (70% of normal) and 3 600KU / L (90% of normal) respectively in patients with blood transfusions and without transfusions, and statistics were made on the differences of serum cholinesterase time. Results: The blood transfusion group in the serum cholinesterase activity restored to 2 800KU / L and more than 3 600KU / L less time than the blood transfusion group, the difference was statistically significant (P <0.01), two groups of patients from the atropine Needed time difference was not statistically significant (P> 0.05). Conclusion: The transfusion of acute organophosphorus pesticide poisoning can significantly improve the recovery rate of serum cholinesterase activity, but has no significant effect on the time from atropine, which has no significant effect on the course of the disease.