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目的:利用X线头颅定位侧位片上颈椎的增龄性指标并将其定量化,建立第三、四颈椎的定量化增龄指标与骨龄之间的相关回归方程,为正畸临床上判定患者的骨龄及成熟度提供理论依据。方法:华中地区青少年研究样本158例(男80例,女78例)。根据颈椎体与骨龄相关的增龄性变化,提出第三和第四颈椎体相关的十二个指标,对纳入样本的X线头颅定位侧位片颈椎影像进行定量化测量,并用逐步多元回归分析检验增龄性定量指标与骨龄的相关性。结果:统计学显示骨龄和颈椎定量化指标呈高度相关,同时具有性别差异。获得不同性别相关线性回归方程,男性:Age=-0.528+4.534PH/AP3+1.463AH/H4+5.364AH/AP3-1.894AH/PH4+3.345AH/H3;女性:Age=1.679+5.503AH/AP3+3.432AH/H4+3.528H/PH3-3.278PH/AP4+2.502AH/H3(其中男性r2=0.96;女性r2=0.97)。结论:华中地区青少年人群颈椎发育上存在性别差异,提示在进行骨龄判断时应考虑性别因素。利用定量的颈椎增龄性指标判定骨龄精确性高,具有统计学意义。
OBJECTIVE: To establish the age-related index of cervical vertebrae in the lateral radiographs by X-ray and quantitatively establish the correlation regression equation between the quantitative age-increasing index and the bone age of the third and fourth cervical vertebrae. Bone age and maturity provide the theoretical basis. Methods: A total of 158 adolescent studies in central China (male 80 and female 78) were included. According to age-related changes of cervical vertebrae and bone age, the third and fourth cervical vertebral body associated with the twelve indicators of the sample included in the X-ray lateralization of the cervical spine image quantitative measurement and stepwise multiple regression analysis Test age-related quantitative indicators of bone age. Results: Statistical analysis showed that bone age and cervical quantitative indicators are highly correlated with gender differences. Age = -0.528 + 4.534PH / AP3 + 1.463AH / H4 + 5.364AH / AP3-1.894AH / PH4 + 3.345AH / H3; Female: Age = 1.679 + 5.503AH / AP3 + 3.432AH / H4 + 3.528H / PH3-3.278PH / AP4 + 2.502AH / H3 (male r2 = 0.96; female r2 = 0.97). Conclusion: There are gender differences in cervical development among adolescents in Central China, suggesting that gender should be taken into account when judging bone age. The use of quantitative cervical age index to determine the accuracy of bone age, with statistical significance.