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讨论本例特点:①患者男性,36岁。②病初表现为头昏、乏力、贫血,骨髓检查证实为红系再障。住院一年输血3万ml。曾出现过黄疸及肝功异常。③病程中出现多饮、多尿、多食。查血糖436mg%,尿糖卅。④4年来不规则畏寒、发热、多次血培养阴性,抗生素治疗无效,无皮疹及淋巴结肿大。⑤皮肤色素加深,以眼眶及小腿皮肤最明显,呈青铜色。⑥实验室检查γ—球蛋白增高,IgG、IgA高,免疫复合物阳性。⑦血清铁高,铁蛋白高,尿含铁血黄素阳性。吴国梁主任军医:根据以上病史分析,患者原发病为纯红再障,治疗中曾大量输血,总量达3万ml,此后一度发生肝功损害。再次入院时见面色灰暗,两眼眶周围皮肤青铜色,两小腿皮肤发黑,肝肿大,血糖、尿糖均升
Discussion of this case features: ① male patient, 36 years old. ② early symptoms of dizziness, fatigue, anemia, bone marrow examination confirmed erythroid aplastic anemia. Hospitalized blood transfusion 30,000 ml a year. Had jaundice and abnormal liver function. ③ appear in the course of drinking, polyuria, eat more food. Check blood sugar 436mg%, urine sugar 卅. ④ 4 years irregular chills, fever, blood culture negative many times, antibiotic treatment ineffective, no rash and swollen lymph nodes. ⑤ skin pigment deepening, the most obvious eye and leg skin, bronze. ⑥ laboratory tests γ-globulin increased, IgG, IgA high, immune complex positive. ⑦ serum iron high, high ferritin, urine hemosiderin positive. Wu Guoliang director of the military: According to the above history analysis, patients with primary disease is pure red aplastic anemia, treatment has a large number of blood transfusions, the total amounted to 30000 ml, since liver dysfunction occurred. Seeing dark gray on admission to hospital again, the skin around the two eyes was bronze, the skin of both legs became black, hepatomegaly, blood sugar and urine sugar both rose