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目的观察卡托普利治疗慢性心力衰竭的临床疗效。方法将84例慢性心力衰竭分为治疗组54例,对照组30例,两组均予常规强心、利尿治疗,而治疗组在此基础上加用卡托普利治疗。治疗前后分别进行心功能(NYHA)分级评估,并进行观察心率、呼吸、肝脏、下肢水肿的变化。结果与治疗组相比,治疗10~14 d后,两组的心功能分级明显改善,且治疗组较对照组改善更明显,(P<0.05)。结论结果提示卡托普利治疗慢性心力衰竭疗效明显,是一种安全有效的治疗方法。
Objective To observe the clinical efficacy of captopril in the treatment of chronic heart failure. Methods Eighty-four patients with chronic heart failure were divided into treatment group (n = 54) and control group (n = 30). Both groups were given conventional cardioplegia and diuresis, while the treatment group was treated with captopril. Heart function (NYHA) was assessed before and after treatment, and changes of heart rate, respiration, liver and lower extremity edema were observed. Results Compared with the treatment group, after 10 to 14 days of treatment, the cardiac function scores of the two groups were significantly improved, and the improvement of the treatment group was more obvious than that of the control group (P <0.05). Conclusions The results suggest that captopril treatment of chronic heart failure has obvious curative effect and is a safe and effective treatment.