Eosinophilic esophagitis(EoE)is a chronic immune-and antigen-mediated disease caused by infiltration of eosino-phils in esophagus tissue,which leads to morphological and functional abnormalities at this site[1].This disease was discovered in 1995 by Kelly et al.[2];since then,it has become increasingly recognized and discussed by research-ers[2,3].EoE affects children and adults and is three times more prevalent in males than in females.According to a recent systematic review,there are 19.1 cases of EoE per 100,000 children/year,with a higher frequency in Western countries[4].