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目的:探讨脑内多发性硬化(MS)的核磁共振(MRI)诊断价值。方法:回顾性分析48例经临床确诊为MS患者的MRI表现及相关资料。48例均行MRI常规平扫,46例加做增强扫描。结果:(1)病灶多发,主要分布于侧脑室周围及额、颞、顶、枕叶皮层下白质区,部分累及胼胝体、小脑、脑干、丘脑、基底节及大脑皮质;双侧侧脑室旁可见“垂直脱髓鞘征”;(2)病灶主要以长和较长T2、略长和等T1信号为主;(3)增强扫描显示强化与不强化病灶同时存在,强化病灶呈点状、斑片及环形;少数急性起病病例病灶呈较均匀一致的强化。结论:MRI是临床诊断MS的敏感、直观、最有价值的检查手段。
Objective: To investigate the diagnostic value of intracranial multiple sclerosis (MS) by magnetic resonance imaging (MRI). Methods: The MRI findings and related data of 48 clinically diagnosed MS patients were retrospectively analyzed. 48 cases were performed conventional MRI plain scan, 46 cases plus enhanced scan. Results: (1) The lesions were multiple and mainly distributed around the lateral ventricle and in the white matter area of the frontal, temporal, apex and occipital lobe, and partially involved the corpus callosum, cerebellum, brain stem, thalamus, basal ganglia and cerebral cortex; bilateral Visible “vertical demyelination syndrome ”; (2) lesions mainly in long and long T2, slightly longer and equal T1 signal; (3) enhanced scan showed enhanced and non-enhanced lesions coexist, Like, patch and ring; a small number of acute onset lesions were more uniform and consistent enhancement. Conclusion: MRI is a sensitive, intuitive and valuable diagnostic tool for clinical diagnosis of MS.