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5. Open Sesame： treasure in store-operated calcium entry pathway for cancer therapy

Open Sesame： treasure in store-operated calcium entry pathway for cancer therapy

来源 :中国科学：生命科学英文版 | 被引量 : 0次 | 上传用户：fencer_200

【摘 要】

：

Store-operated Ca2+ entry(SOCE) controls intracellular Ca2+ homeostasis and regulates a wide range of cellular events including proliferation,migration and inva

【作 者】

：

PAN Zui 

【机 构】

：

DepartmentofInternalMedicine,DepartmentofSurgery,ComprehensiveCancerCenter,DavisHeartandLungResearch

【出 处】

：

中国科学：生命科学英文版

【发表日期】

：

2015年1期

【关键词】

：

癌症治疗 细胞内钙 病理生理作用 操纵 宝藏 开门 芝麻 STIM Orai1 STIM1 Ca2＋ oscillations proliferation me 

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论文部分内容阅读

Store-operated Ca2+ entry(SOCE) controls intracellular Ca2+ homeostasis and regulates a wide range of cellular events including proliferation,migration and invasion.The discovery of STIM proteins as Ca2+ sensors and Orai proteins as Ca2+ channel pore form

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