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水苏碱是中药益母草的主要成分之一,益母草全草含生物碱0.11%~2.09%,其中水苏碱为0.59%~1.72%,为其主要成分,目前上市的益母草口服液、益母草颗粒、益母草膏等,均以水苏碱作为质量控制的指标性成分,水苏碱亦能人工合成,近年来其药理研究比较丰富。本文通过检索近10年国内外有关水苏碱的药理研究文献,综述水苏碱的药理活性,结果显示水苏碱具有兴奋子宫、抗炎、改善血液流变学、抗血栓等多种药理作用,提示具有开发价值,也为其进一步开发提供参考。
Stachydrine is one of the main constituents of Chinese traditional medicine Motherwort, the whole plant of Motherwort contains alkaloids 0.11% ~ 2.09%, of which stachydrine 0.59% ~ 1.72%, as its main component, currently listed Motherwort Oral Liquid, Motherwort granules, Motherwort ointment, are stachydrine as an indicator of quality control components, stachydrine can also be synthesized in recent years, its rich pharmacological research. In this paper, we reviewed the pharmacological studies on stachydrine in the past 10 years and reviewed the pharmacological activities of stachydrine. The results showed that stachydrine has a variety of pharmacological effects such as excited uterus, anti-inflammation, hemorrheology, and anti-thrombosis , Suggesting that the development of value, but also for its further development to provide a reference.