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目的探讨翼状胬肉切除联合自体结膜瓣膜移植术对泪膜稳定性的影响。方法研究共纳入86例单眼翼状胬肉患者，就诊时间2011年7月~2014年4月，所有患者均行翼状胬肉切除联合自体结膜瓣移植术。分别于术前1wk；术后2wk；1mo，3mo行双眼泪膜功能检查，包括泪液分泌试验(Schirmer I test，SIt)、泪膜破裂时间(break-up time, BUT)、角膜荧光色染色评分(corneal fluoresescein staining，CFS)。设手术眼为研究组,对侧眼为对照组。结果 Schirmer I test：研究组与对照组相比，术前及术后各个阶段两组之间均无显著性差异(>0.05)；BUT：两组术前1wk与术后2wk，1mo比较均有显著性差异(0.05)；CFS：两组比较术前及术后各个时间点比较均有显著性差异(均0.05). The results of BUT was significantly dif erent in the eyes between the two groups 1week before,and two weeks and 1 month after surgery( 0.05). There were significantly dif erence in the results of CFS between two groups at any time in the study ( >0.05). Conclusion Tear film stability was broken in the eyes with pterygium. Pterygium excision combined with conjunctival autograft transplantation can obviously restore the tear film function into normal state.