多年来,不少作者均认为青光眼患者眼球及视神经的病理改变和血管的改变有关,并指出眼压高的眼球,血管有明显的病理改变。1954年 Duke-Elder 亦认为引起贫血的因素如视神经小动脉硬化可致视神经海绵状变性。1951年 Walff 使视神经乳头、视神经、视网膜动脉血循环减少,来说明上述相同的见解。 Over the years, many authors believe that glaucoma patients with ocular and optic nerve pathological changes and changes in blood vessels, and pointed out that high intraocular pressure of the eye, blood vessels have obvious pathological changes. 1954 Duke-Elder also believes that anemia caused by factors such as arteriosclerosis can cause optic nerve spongiform degeneration. Walff in 1951 to the optic nerve papilla, optic nerve, retinal artery blood circulation reduction, to illustrate the same opinion.