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原发性胆汁性肝硬变(PBZ)是一种慢性进行性肝病,病因不明,主要累及中年妇女。人们曾进行多种检查,目的在于探索具有决定意义的细胞(自身)抗原并查明其特征。但我们对于细胞损伤的细胞性及体液性效应机制尚所知甚少,同时对于 PBZ 时组织改变的典型的空间和时间分布也不清楚。尚不清
Primary biliary cirrhosis (PBZ) is a chronic progressive liver disease of unknown etiology, mainly involving middle-aged women. A number of tests have been conducted with the aim of exploring and determining the characteristics of the cellular (self) antigen of decisive significance. However, little is known about the cellular and humoral effector mechanisms of cell injury, and the typical spatial and temporal distribution of tissue changes at the time of PBZ is unclear. Not clear