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真菌性角膜溃疡是一种致盲率较高、治疗极棘手的感染性眼病。我国作为农业大国,从事农业生产的人口众多,农业性眼外伤,尤其是以植物性眼外伤多见。农药及化肥的广泛使用,使土壤中的腐生寄生菌的拮抗菌减少,从而使镰刀菌等真菌大量滋生。此外,滥用糖皮质激素和广谱抗生素,使机体菌群失衡,也会增加真菌感染的机会。如何最大限度地保留患者宝贵的视力,是我们目前的研究课题。我科自2004年11月~2007年10月应用碘酊烧灼联合氟康唑与消朦片治疗真菌性角膜溃疡30例,取得了满意效果。
Fungal corneal ulcer is a blinding rate of high, the treatment of intractable infectious eye disease. As a large agricultural country in our country, there are a large population of agricultural production and agricultural ocular trauma, especially in plant ocular trauma. The widespread use of pesticides and fertilizers reduces the amount of antagonistic bacteria in the saprophytic parasites of the soil, resulting in the massive breeding of fungi such as Fusarium. In addition, the abuse of glucocorticoids and broad-spectrum antibiotics, the imbalance in bacterial flora, but also increase the chance of fungal infections. How to maximize the retention of the patient’s valuable sight is our current research topic. Our department from November 2004 to October 2007 iodine tincture cautery in combination with fluconazole and eliminate diminishing tablets in 30 cases of fungal corneal ulcer, and achieved satisfactory results.