论文部分内容阅读
对24例初诊2型糖尿病患者进行胰岛素泵治疗10~14天。结果:治疗后空腹(FBG)及餐后血糖(PBG)均明显下降(P<0.001),HbA1c明显下降(P<0.05),HomaB明显上升、HomaIR明显下降、ΔI30/ΔG30明显升高(P<0.01),其中11例仅控制饮食和运动治疗随访6月后HbA1c 5.99±0.57、FBG 6.2±1.1mmol/L、PPG 7.8±2.4mmol/L。结论:胰岛素泵治疗能尽快解除高糖毒性,显著恢复胰岛β细胞功能,减轻胰岛素抵抗。
24 patients with newly diagnosed type 2 diabetes were treated with insulin pump for 10 to 14 days. Results: FBG and postprandial blood glucose (PBG) were significantly decreased (P <0.001), HbA1c was significantly decreased (P <0.05), HomaB was significantly increased, HomaIR was significantly decreased and ΔI30 / ΔG30 was significantly increased (P < 0.01). Of the 11 patients, only HbA1c 5.99 ± 0.57, FBG 6.2 ± 1.1mmol / L, and PPG 7.8 ± 2.4mmol / L after 6 months of diet and exercise control. Conclusion: Insulin pump can relieve the hyperglycemia as soon as possible, remarkably restore the islet β cell function and reduce the insulin resistance.