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已证实在许多疾病(包括某些恶性肿瘤)有循环免疫复合物(CIC)存在,其中几种疾病所发生的炎症反应和血管损害被认为是CIC形成和沉着的结果。但对在癌症时CIC的作用了解甚少,有人提出CIC可能通过转变宿主对恶性肿瘤细胞免疫应答的有效性而加速肿瘤的发展。虽然缺乏直接的证据,但是临床研究确实表明CIC的存在与肿瘤的凶险经过之间有相关。作者早期研究已表明成人急性白血病诊断时有血清CIC存在的患者的预后较无CIC者差。本研究旨在更清楚
It has been demonstrated that circulating immune complexes (CICs) exist in many diseases, including certain malignancies, and inflammation and vascular damage occurring in several of these diseases are believed to be the result of CIC formation and sedation. However, little is known about the role of CIC in cancer. It has been suggested that CIC may accelerate the development of tumors by altering the host’s effectiveness in response to malignant tumor cells. Although there is no direct evidence, clinical studies do show that there is a correlation between the presence of CIC and the dangerous progression of the tumor. Early studies by the authors have shown that patients with serum CIC at diagnosis of adult acute leukemia have a worse prognosis than those without CIC. This study aims to make it clearer