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目的:分析寻乌县人民医院抗菌药物使用现状和存在问题,并提出相应的合理使用的干预对策。方法:抽取2012年1月—2013年9月间门诊和住院患者病历750例,按照用药目的分为常规治疗组、手术预防组和感染治疗组,分析其抗菌药物使用存在的问题,并研究合理用药的措施。结果:抗菌药物的使用率最高的是氨苄西林-舒巴坦钠,占26.27%;药物利用指数(drug utilization index,DUI)为1.25,经分析其差异有统计学意义(P<0.05);抗菌药物的使用总安全率最低的是常规治疗组,为53.10%,与其他两组比较,其差异有统计学意义(P<0.05)。结论:抗菌药物的不合理使用现象较为突出,临床应采取多种干预措施,确保用药安全有效。
Objective: To analyze the current situation and existing problems of antimicrobial use in Xunwu People’s Hospital, and to propose corresponding intervention measures for rational use. Methods: A total of 750 medical records of outpatients and inpatients from January 2012 to September 2013 were collected and divided into routine treatment group, operation prevention group and infection treatment group according to the purpose of treatment, and the problems existing in the use of antimicrobial agents were analyzed, and the reasonable Medication measures. Results: The highest use rate of antibacterials was ampicillin-sulbactam sodium (26.27%). The drug utilization index (DUI) was 1.25. The difference was statistically significant (P <0.05) The lowest overall safety of drug use was in the conventional treatment group, which was 53.10%, which was significantly different from the other two groups (P <0.05). Conclusion: The phenomenon of unreasonable use of antimicrobial drugs is more prominent, clinical interventions should be taken to ensure safe and effective drug use.