恶性肿瘤的发生、发展、浸润及转移是一个相当复杂的过程,也是多因素参与的过程,其中一些生物学因子发挥了关键性作用。自20世纪90年代以来,许多学者致力于对组织蛋白酶D(Cathepsin D,Cath-D)的研究,Cath-D与许多恶性肿瘤大小、分化程度、转移和预后密切相关,尤其在乳腺癌方面, The occurrence, development, infiltration and metastasis of malignant tumors are a complicated process and a multi-factor involved process. Some of these biological factors play a key role. Since the 1990s, many scholars have devoted themselves to the study of Cathepsin D (Cath-D). Cath-D is closely related to the size, differentiation, metastasis and prognosis of many malignant tumors, especially in breast cancer.