IL－12是由巨噬细胞和B细胞产生的细胞因子，IL－12是NK细胞、T细胞产生IFN－γ强有力的诱导剂。虽然最近报道IL－12在体内能强化已建立的TH2免疫应答，但IL－12对TH2细胞因子产生的影响还不清楚。该文采用分离外周血T细胞、人T细胞系和T细胞克隆的建立及特性鉴定，诱导产生细 IL-12 is a cytokine produced by macrophages and B cells, which is a potent inducer of IFN-γ by T cells. Although it has recently been reported that IL-12 potentiates the established TH2 immune response in vivo, the effect of IL-12 on TH2 cytokine production is unclear. This article uses the separation of peripheral blood T cells, human T cell lines and T cell clones established and characterization, induction of fine