遗传因素为耳硬化症的病因之一,一般认为耳硬化症家族中,有耳聋者比例较大,孪生子同患此病亦不少见,国内少见家族高发此病的报告。我们曾见一个家族中,虽然家庭人员分散,未便家系调查,但兄弟及其子女四人同患耳硬化症,其中三人并经手术证实,很显然他们的发病与遗传因素有关。例一,何某,男,48岁,1974年11月21日入院,患者诉十多年来双耳进行性耳聋,1966年以来加重,右侧较著,伴低调耳鸣,经多方治疗无效,以往身体健康。 Genetic factors for one of the causes of otosclerosis, generally believed that the family of ear sclerosis, a larger proportion of deaf, the twin is not uncommon with the disease is not uncommon, the domestic rare family high incidence of the disease report. We have seen a family with four families and two brothers and their children suffering from ear sclerosis. Although three families were confirmed by surgery, it is clear that their incidence is related to genetic factors although their family members are scattered and inconvenient to investigate the pedigree. Example 1, Hemou, male, 48 years old, admitted to hospital on November 21, 1974, the patient complained of deafness in both ears for more than ten years, aggravated since 1966, right-sided, accompanied by low-key tinnitus, Healthy body.