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铜绿假单胞菌能通过产生多种 β 内酰胺酶、改变细菌外膜的渗透性及各种主动泵出系统以及形成生物膜而对抗生素产生耐受性 ,本文就其对临床上应用最广的 β 内酰胺类抗生素耐药机制的研究进展做一综述
Pseudomonas aeruginosa is able to produce antibiotic resistance by producing a variety of beta-lactamases, altering the permeability of bacterial outer membranes and various active pump-out systems, and biofilm formation. This article is the most widely used in clinical practice Β-lactam antibiotic resistance mechanism of the research progress is reviewed