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作者观察了557例肺癌病人,都是经活检或尸体解剖组织学检查确诊的。比较了痰液和经支气管镜或支气管导管(不经支气管镜)取得支气管分泌物的细胞学检查的结果。结果显示支气管分泌物的癌细胞检出率为78.1％,痰液检出率62.3％(P<0.001)。痰液检查平均每一病人需3.8次才能获得阳性结果,而支气管分泌物检查则平均1.4次即获得阳性结果。痰液检查的方法也比支气管分泌物检查更为困难。作者建议对怀疑肺癌的住院病人最好先行支气管镜及支气管导管检查取支气管分泌物进行细胞学检查。阴性时再连续进行3～5次每日痰液检查,这种综合检查结果,癌细胞的检出率最高(80.1％)。如果支气管镜检查有禁忌,或X线所见无法定位,一开始就只能做痰液检查。作者又对271例肺癌病人进行了组织学检查(活
The authors observed 557 patients with lung cancer who were diagnosed by biopsy or autopsy. The results of cytological examination of sputum and bronchial secretions obtained by bronchoscopy or bronchoscopy (without bronchoscopy) were compared. The results showed that the detection rate of bronchial secretions was 78.1% and the sputum detection rate was 62.3% (P<0.001). On average, each patient required 3.8 injections to obtain a positive result, while the bronchial secretions test showed an average of 1.4 positive results. The method of sputum examination is also more difficult than the examination of bronchial secretions. The authors recommend that bronchoscopy and bronchoscopy should be performed on hospitalized patients suspected of lung cancer to obtain bronchial secretions for cytological examination. When it is negative, 3 to 5 consecutive sputum examinations are performed continuously. The results of this comprehensive examination show that the detection rate of cancer cells is the highest (80.1%). If the bronchoscopy is contraindicated or cannot be located on the X-ray, the sputum examination can only be performed at the beginning. The author also performed histological examination of 271 patients with lung cancer (live