脾脏肿大是伤寒常见的症状之一,往往是轻度或中度肿大。近年来,由于医疗条件改善,伤寒发生巨大脾脏者甚为少见,我们在1978年8月26日收治一例伤寒巨脾者,当时误诊为胰腺肿瘤收住外科,后转内科确诊为伤寒。男,46岁。不规则发烧伴有畏寒、腹泻、消瘦一个半月,无腹痛,有腹胀,大便每日4～5次,稀软便,偶有水样便,无脓血,食欲不振,无恶心呕吐,伴有头痛、头晕,无胸痛,无咳嗽心慌气 Splenomegaly is one of the common symptoms of typhoid fever, often mild or moderate swelling. In recent years, due to improved medical conditions, typhoid fever, a huge spleen is very rare, we were on August 26, 1978 admitted to a typhoid spleen who was misdiagnosed as pancreatic cancer in the surgery, later transferred to medical diagnosis of typhoid fever. Male, 46 years old. Irregular fever with chills, diarrhea, weight loss a month and a half, no abdominal pain, abdominal distension, stool 4 to 5 times a day, loose stool, occasional watery stools, no sepsis, loss of appetite, no nausea and vomiting, with Have a headache, dizziness, no chest pain, no cough palpitation