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目的:观察丹参注射液和“活血化瘀汤”结合中医辨证治疗原发性肾病综合征(PNS)的疗效。方法:64例PNS患者随机分为2 组,对照组(30 例)采用泼尼松治疗;治疗组(34 例)在激素治疗的基础上加用丹参注射液20 m l加入5% 葡萄糖250 m l中静滴,并口服“活血化瘀汤”治疗。结果:治疗组血胆固醇及全血粘度下降明显,与对照组比较均有显著性差异(P< 0.05或P< 0.01);治疗组总有效率为94.1% ,对照组为83.3% ,2 组比较有显著性差异(χ2= 5.76,P< 0.05)。结论:“活血化瘀汤”和丹参注射液联用激素是治疗PNS的有效方法。
Objective: To observe the effect of Danshen injection and “Huoxue Huayu Decoction” combined with traditional Chinese medicine in the treatment of primary nephrotic syndrome (PNS). Methods: Sixty-four patients with PNS were randomly divided into two groups. The control group (30 cases) was treated with prednisone. In the treatment group (34 cases), 20 ml of Danshen injection was added on the basis of hormone therapy. l intravenous infusion, and oral “blood circulation” treatment. Results: The blood cholesterol and whole blood viscosity of the treatment group decreased significantly compared with the control group (P <0.05 or P <0.01). The total effective rate was 94.1% in the treatment group and 83.3%. There was significant difference between the two groups (χ2 = 5.76, P <0.05). Conclusion: “Huoxue Huayu Decoction” combined with Danshen injection is an effective method to treat PNS.