作者在筛选抗曼氏血吸虫病药物时。发现金刚烷基氨乙硫醇有效,继而用感染曼氏血吸虫病的小鼠,研究了氨乙硫醇类化合物的抗血吸虫作用和化学结构的关系。药物在初筛时仅采用卵谱法,动物每天给服1/5LD_(50)的剂量,连续5天。复筛时动物给服药 The authors screen for anti-human schistosomiasis drugs. It was found that adamantanethylaminoethanethiol was effective, and then the mice infected with Schistosoma mansoni were used to study the relationship between the anti-schistosomiasis and the chemical structure of the aminoethanethiol compounds. Drugs used in the screening only the egg spectrum method, the animals daily dose of 1 / 5LD_ (50) for 5 days. Animals were given medication when rescaled