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目的:观察百令胶囊联合羟苯磺酸钙对早期糖尿病肾病的疗效。方法:72例患者随机分为羟苯磺酸钙治疗组,百令胶囊治疗组、羟苯磺酸钙和百令胶囊联合用药组,疗程为12周,比较三组基质金属蛋白酶2(MMP2)、尿白蛋白排泄率(UAER)指标变化。结果:三组患者治疗后UAER均有不同程度下降,C组下降更为显著。结论:百令胶囊联合羟苯磺酸钙降低尿蛋白的疗效显著。
Objective: To observe the effect of Bailing capsule and calcium dobesilate on early diabetic nephropathy. Methods: Seventy two patients were randomly divided into calcium dobesilate group, Bailing capsule group, calcium dobesilate group and Bailing capsule group for 12 weeks. The levels of matrix metalloproteinase 2 (MMP2) , Urinary albumin excretion rate (UAER) index changes. Results: After treatment, UAER decreased in all three groups, but in C group decreased more significantly. Conclusion: Bailing capsule combined with calcium dobesilate has a significant effect in reducing urinary protein.