论文部分内容阅读
目的:探讨基层社区高血压病人群联合使用硝苯地平缓释片和依那普利治疗的效果。方法:选择我社区中心所辖区域内高血压病患者150例,随机分为两组,硝苯地平缓释片联合依那普利治疗组75例,单用依那普利对照组75例,观察疗效,并观察对心率、血脂、血糖、肾功能的影响。结果:治疗8周后,治疗组总有效率达94.7%,对照组总有效率72%,治疗组降压效果显著高于对照组,两组间比较差异有统计学意义。两组治疗前后心率、血脂、血糖、肾功能无明显变化。结论:硝苯地平缓释片联合依那普利降压达标率较高,不良反应发生率低,且价格便宜,适合广大基层社区人群中的高血压病患者选择。
Objective: To investigate the effect of combination of nifedipine sustained-release tablets and enalapril on the community-based hypertensive patients. Methods: One hundred and fifty cases of hypertension in our community center were randomly divided into two groups: nifedipine sustained-release tablets and enalapril-treated group, 75 cases of enalapril-alone control group, Observation of efficacy, and observed on heart rate, blood lipids, blood glucose, renal function. Results: After 8 weeks of treatment, the total effective rate was 94.7% in the treatment group and 72% in the control group. The antihypertensive effect in the treatment group was significantly higher than that in the control group, with significant difference between the two groups. Before and after treatment, heart rate, blood lipid, blood glucose, renal function no significant change. Conclusion: The compliance rate of nifedipine sustained-release tablets combined with enalapril is lower, the incidence of adverse reactions is low, and the price is cheap, which is suitable for the patients with hypertension in the grass-roots community population.