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目的探讨单用盐酸坦索罗辛治疗良性前列腺增生(BPH)的效果。方法单独应用盐酸坦索罗辛治疗BPH20例。治疗前及治疗7 d、治疗3个月时进行国际前列腺症状评分(IPSS评分)和生活质量指数评分(QOL评分),评价其变化。结果两组患者均有效。治疗7 d时,IPSS评分和QOL评分与治疗前相比差异均有统计学意义;治疗3个月时,IPSS评分和QOL评分与治疗前相比差异有统计学意义(P<0.05),和治疗7 d时相比较差异无统计学意义。中度症状组逆行射精1例,重度症状组血压下降1例,无其他并发症。结论单独应用盐酸坦索罗辛治疗BPH患者,高效、安全、不良反应小。
Objective To investigate the effect of tamsulosin hydrochloride alone on benign prostatic hyperplasia (BPH). Methods Twenty patients with BPH were treated with tamsulosin hydrochloride alone. Prostate symptoms score (IPSS) and quality of life index (QOL) scores were evaluated before treatment and 7 days after treatment for 3 months. Results Both groups were effective. The IPSS score and QOL score were significantly different from those before treatment at 7 days of treatment. IPSS score and QOL score at 3 months after treatment were significantly different from those before treatment (P <0.05), and There was no significant difference between the 7th day and the 7th day after treatment. 1 case of retrograde ejaculation in moderate symptom group, 1 case of decrease in blood pressure in severe symptom group, no other complications. Conclusion Tamsulosin hydrochloride alone is effective, safe and has a small adverse reaction.