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目的：为了解四川泸州地区庚型肝炎病毒（HGV）流行情况，方法：根据发表的HGV序列非编码区（NCR）设计两对引物，用RT-套式PCR方法，结果：对102例各型肝炎病人血清进行检测，发现39例HGV-RNA阳性，阳性率为38.23％。其中3例（7.69％）HGV-RNA阳性者为非A-E型肝炎，33例（84.61％）为HBV与HGV共同感染，另外3例（7.69％）为HCV和HGV共同感染。结论：提示泸州地区是HGV高流行区。PCR所得产物进行序列测序，结果表明，“泸州株”HGV非编码区与“中国株”同源性达89.4％，与“重庆株”同源性达94.3％，提示“泸州株”和“重庆株”可能为相同亚型。
Objective: To understand the prevalence of hepatitis G virus (HGV) in Luzhou, Sichuan Province. Methods: Two pairs of primers were designed according to the published non-coding region of HGV sequence (NCR) Hepatitis patients sera were detected and found that 39 cases of HGV-RNA positive, the positive rate was 38.23%. Three of the HGV-RNA positive cases (7.69%) were non-A-E hepatitis and 33 (84.61%) were co-infected with HBV and HGV. The other three cases (7.69%) were co-infected with HCV and HGV. Conclusion: It is suggested that Luzhou is a HGV endemic area. The results of sequencing showed that the homology of HGV non-coding region of Luzhou strain with that of Chinese strain was 89.4% and that of Chongqing strain was 94.3%, which indicated that Luzhou strain and Chongqing Strains "may be the same subtype.