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本文报道22例不能切除的原发性肝癌行肝动脉插管化疗,其中6例配合肝动脉检塞,4例肝动脉结扎。临床分期Ⅱ期19例,Ⅲ期3例,动脉灌注药物6例单用乌头碱,4例单用5-Fu,l2例用乌头碱配合5-Fu治疗。治疗结果:治疗后中数生存期为6.6个月,3个月、半年和1年生存率分别为81.3％、50％、和13.6％。认为肝动脉插管化疗,特别配合肝动脉检塞或结扎是治疗不能切除的原发性肝癌的一种有效、安全的姑息疗法。
This article reported 22 cases of unresectable primary hepatic carcinoma with hepatic arterial catheterization chemotherapy, of which 6 cases were combined with hepatic artery occlusion and 4 cases with hepatic artery ligation. There were 19 cases with clinical stage II and 3 cases with stage III. 6 cases of arterial infusion drugs used aconitine alone, 4 cases used 5-Fu alone, and l2 cases were treated with aconitine plus 5-Fu. Treatment outcomes: The median survival time after treatment was 6.6 months, with 3 months, 6 months, and 1 year survival rates of 81.3%, 50%, and 13.6%, respectively. Hepatic arterial intubation chemotherapy, especially with hepatic artery thrombosis or ligation, is considered to be an effective and safe palliative treatment for unresectable primary liver cancer.