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目的无创正压通气(NIPPV)治疗老年慢性阻塞性肺疾病(COPD)并II型呼吸衰竭的临床价值。方法住院老年COPD并呼吸衰竭62例,其中对照组30例,用常规治疗。治疗组32例,除常规治疗外,用口鼻面罩进行NIPPV。结果NIPPV治疗1d后pH、PaO2上升及PaCO2下降(P<0.05);对照组治疗3d后pH、PaO2值上升及PaCO2下降(P<0.01)。治疗组呼吸衰竭纠正时间及住院时间缩短且呼吸衰竭缓解率高(P<0.05)。结论早期合理的应用NIPPV可以纠正呼吸肌疲劳,提前改善症状及血气分析结果,是治疗老年COPD并呼吸衰竭的重要手段。
Objective The clinical value of noninvasive positive pressure ventilation (NIPPV) in the treatment of senile chronic obstructive pulmonary disease (COPD) and type II respiratory failure. Methods In hospitalized elderly patients with COPD and respiratory failure in 62 cases, of which 30 cases of control group, with conventional treatment. In the treatment group, 32 cases were treated with NIPPV with a mask of nose and mouth except for routine treatment. Results After 1 day of NIPPV treatment, pH, PaO2 and PaCO2 decreased (P <0.05). After 3 days of treatment, pH and PaO2 increased and PaCO2 decreased (P <0.01). Treatment group respiratory failure correction time and hospitalization time shortened respiratory failure and high remission rate (P <0.05). Conclusion The early and reasonable application of NIPPV can correct respiratory muscle fatigue, improve symptoms and blood gas analysis results in advance, is an important means of treatment of elderly COPD and respiratory failure.