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目的了解四川省2004—2013年恶性肿瘤死亡情况及其所造成的潜在寿命损失,为慢性病防控工作提供参考依据。方法收集四川省2004年1月—2013年12月全人群死因监测点死亡登记报告资料,应用死亡登记信息系统统计与分析工具、Joinpoint 4.2.0.2软件、SPSS 18.0软件分析恶性肿瘤粗死亡率、标化死亡率及其变化趋势和潜在寿命损失年数。结果四川省居民恶性肿瘤死亡率从2004年的129.66/10万上升至2013年的191.09/10万,呈上升趋势(APC=4.57%,t=11.84,P<0.01),标化死亡率从2004年的122.58/10万上升至2013年的130.48/10万,上升趋势无统计学意义(P>0.05);男性恶性肿瘤死亡率高于女性,死亡率性别比为1.95~2.17:1,标化死亡率性别比为1.85~2.05∶1;2004—2013年居于四川省前10位的恶性肿瘤依次为肺癌、肝癌、食管癌、胃癌、结直肠癌、白血病、乳腺癌、鼻咽癌、膀胱癌、宫颈癌,除胃癌外的其他9种恶心肿瘤死亡率均呈上升趋势(均P<0.05);四川省2004、2009、2013年恶性肿瘤所致居民潜在寿命损失年数(YPLL)分别为157 532.0、204 171.0、196 413.0人年,潜在寿命损失率(YPLLR)分别为14.04%、16.93%、15.83%。结论四川省恶性肿瘤死亡率总体呈上升趋势,肺癌、肝癌、食管癌是造成该地区潜在寿命损失的主要恶性肿瘤。
Objective To understand the death of malignant tumor in 2004-2013 in Sichuan Province and its potential loss of life expectancy and provide a reference for prevention and control of chronic diseases. Methods The death registration data of all death toll monitoring stations in Sichuan province from January 2004 to December 2013 were collected. The statistics of the death registration information system and statistical analysis tool, Joinpoint 4.2.0.2 software and SPSS 18.0 software were used to analyze the crude mortality rate of malignant tumor, Mortality and its changing trend and years of potential life loss. Results The mortality rate of malignant tumor in Sichuan province increased from 129.66 / 100000 in 2004 to 191.09 / 100000 in 2013, with an upward trend (APC = 4.57%, t = 11.84, P <0.01) (122.58 / 100000 in 2013, up to 130.48 / 100000 in 2013, the upward trend was not statistically significant (P> 0.05); the mortality of male malignant tumor was higher than that of female, the sex ratio of death was 1.95-2.17: 1, The sex ratio of death was between 1.85 and 2.05: 1. The top ten malignant tumors in Sichuan province from 2004 to 2013 were lung cancer, liver cancer, esophageal cancer, gastric cancer, colorectal cancer, leukemia, breast cancer, nasopharyngeal cancer, bladder cancer , Cervical cancer, and other 9 kinds of nausea cancer except gastric cancer showed an upward trend (all P <0.05). The YPLL of residents with malignant tumors in Sichuan province in 2004, 2009 and 2013 were 157 532.0 , 204 171.0,196 413.0 person-years, and the potential loss of life expectancy (YPLLR) was 14.04%, 16.93% and 15.83% respectively. Conclusion The overall mortality rate of malignant tumors in Sichuan Province is on the rise. Lung cancer, liver cancer and esophageal cancer are the major malignant tumors that cause the potential loss of life expectancy in this area.