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目的探讨支气管扩张合并肺部感染患者经支气管镜下肺泡灌洗和灌洗后局部注射敏感抗生素两种方法的疗效。方法将符合标准的60例支气管扩张合并肺部感染患者,按入院顺序随机分为两组:对照组30例,在常规治疗基础上,经支气管镜下肺泡灌洗后注入沐舒坦;治疗组30例,在常规治疗基础上,支气管镜下肺泡灌洗后局部注入沐舒坦加敏感抗生素。每周2次,入院2周内进行疗效评价,比较疗效。结果对照组总有效率为96.67%,治疗组总有效率为100%,两组差异无统计学意义(P>0.05);两组患者治疗前、后的血气情况比较,差异存在统计学意义(P<0.05),组间比较无统计学意义(P>0.05);咳嗽、咳痰等症状及体征缓解时间比对照组明显减少(P<0.05)。结论支扩合并肺部感染患者经支气管镜下肺泡灌洗后局部注敏感抗生素能较快改善症状,减少住院时间及总住院费用。
Objective To investigate the efficacy of bronchoalveolar lavage combined with local injection of sensitive antibiotics in patients with bronchiectasis and pulmonary infection after bronchoalveolar lavage. Methods According to the standard of 60 patients with bronchiectasis and pulmonary infection, according to the order of admission were randomly divided into two groups: the control group of 30 patients on the basis of routine treatment, bronchoalveolar lavage injection of mucosolvan; treatment group 30 For example, on the basis of conventional treatment, local infusion of mucosolvan plus antibiotics after bronchoalveolar lavage. 2 times a week, 2 weeks of admission efficacy evaluation, more effective. Results The total effective rate of the control group was 96.67%, the total effective rate of the treatment group was 100%, there was no significant difference between the two groups (P> 0.05). There was significant difference between the two groups in the blood gas condition before and after treatment P <0.05). There was no significant difference between the two groups (P> 0.05). The symptom such as cough and expectoration and the time of symptom relief were significantly decreased compared with the control group (P <0.05). Conclusions In patients with bronchiectasis and pulmonary infection, local injection of sensitive antibiotics locally after bronchoalveolar lavage can rapidly improve symptoms, reduce hospitalization time and total hospitalization costs.