论文部分内容阅读
目的 探讨青年人胃癌临床病理特点,提高青年胃癌诊治水平,减少误诊误治。方法 对49例青年 胃癌临床特点、组织学特点、治疗预后作回顾性分析,并与中老年人胃癌作对照研究。结果 以消化道症状首发多 见,男女发病之比为1∶1.13,进展期胃癌占92%。组织形态上以低分化癌,印戒细胞癌,粘液腺癌多见占到69%, 明显高于中老年组(P<0.01)。好发于胃底贲门以下,临床误诊30例,2年生存率27%。结论 青年胃癌症状隐 匿,分化程度低,预后差,且易误诊,应及时作胃镜检查,早期诊断为治疗关键。
Objective To investigate the clinical and pathological features of young gastric cancer, improve the diagnosis and treatment of young gastric cancer and reduce misdiagnosis and mistreatment. Methods The clinical features, histological features and prognosis of 49 young patients with gastric cancer were retrospectively analyzed and compared with the gastric cancer in middle-aged and elderly patients. Results The first episode of gastrointestinal symptoms more common, the incidence of men and women was 1: 1.13, 92% of advanced gastric cancer. Tissue morphology to poorly differentiated cancer, signet ring cell carcinoma, mucinous adenocarcinoma more common accounted for 69%, significantly higher than the middle-aged group (P <0.01). Occurred in the stomach below the cardia, clinical misdiagnosis in 30 cases, 2-year survival rate of 27%. Conclusion The symptoms of young gastric cancer are occult, the degree of differentiation is low, the prognosis is poor, and it is easy to be misdiagnosed. Gastroscopy should be done in time and early diagnosis is the key to treatment.