结节病是一种原因不明的非千酪性肉芽肿病变,可侵犯全身多种组织和脏器。过去认为该病主要侵犯肺、淋巴结和皮肤,近年来发现结节病的神经系统病变也不在少数。一般报道神经系统病变的发生率为3.5～5.1%,但根据尸检资料,其发生率可高达14～16%。在神经系统疾病的鉴别诊断中,应提高对本病的认识,现对其病理改变和神经系统表现作一简介。 Sarcoidosis is a non-cheilitis granulomatous disease of unknown cause that can invade a wide range of tissues and organs throughout the body. In the past that the disease mainly affects the lungs, lymph nodes and skin, found in recent years, sarcoidosis is also a rare disease of the nervous system. The general incidence of neurological diseases reported 3.5 to 5.1%, but according to autopsy data, the incidence can be as high as 14 to 16%. In the differential diagnosis of neurological diseases, we should raise awareness of the disease, now its pathological changes and the performance of the nervous system for a brief introduction.