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目的：常见念珠菌种类的临床分析及其对4种抗真菌药物的耐药性。方法：统计近年来临床标本分离的念珠菌并对其进行5-氟胞嘧啶（5-Fc）、两性霉素-B（AMB）、氟康唑（FCA）、伊曲康唑（ITR）的药敏分析。结果：所有分离菌株中白色念珠菌占比最高，为60．1％，其次为光滑念珠菌（20．5％），热带念珠菌（10．9％），克柔念珠菌（4．5％）。体外药敏试验显示AMB和5-Fc对临床常见念珠菌具有比较高的敏感性。结论：白色念珠菌仍是目前第一位感染菌，但非白色念珠菌也不容忽视。不同念珠菌的耐药性存在种间差异。“,”Objective:ToinvestigatetheClinicalspeciesofcommonCandidaspp.andtheirsusceptibilitytoantifungaldrugs. Methods:Statistical analysis of Candida spp.isolated from clinical samples in recent years and their drug sensitivity to 5-fluorocytosine (5-Fc),amphotericin-B (AMB),fluconazole (FCA),itraconazole (ITR).Results:Candida albicans taked up the highest propor-tion of all isolates,up to 60.1%,followed by Candida.glabrata (20.5%),Candida tropicalis (10.9%),Candida krusei (4.5%). In vitro susceptibility test showed AMB and 5-Fc have relatively higher sensitivity.Conclusion:Candida albicans is still the first one in fungi infection,but non-albicans could not be ignored.There are inter-species differences in drug resistance of these Candida spp.