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目的：探讨原发性肝癌TACE介入术后发生感染性并发症的相关危险因素。方法收集2014年1~12月我院诊断原发性肝癌并行TACE介入治疗的730例肝癌病例资料，对21个可能与介入术后感染性并发症发生相关的因素进行单因素分析。对单因素分析差异有统计学意义的因素，采用非条件二元多因素Logistic回归分析其与肝癌术后感染性并发症的相关性。结果730例中41例发生介入术后感染性并发症，介入术后感染性并发症发生率为5.62豫。单因素分析显示：术前合并慢性支气管炎、低白蛋白水平、腹水、异位栓塞及同时行部分脾脏栓塞是肝癌介入术后发生感染性并发症的危险因素(P<0.05)。多因素Logistic回归分析结果显示，合并慢性支气管炎、低白蛋白水平、腹水、异位栓塞及同时行部分脾脏栓塞是发生介入术后感染性并发症的独立危险因素(P<0.05)。结论合并慢性支气管炎、低白蛋白水平、腹水、异位栓塞及同时行部分脾脏栓塞是肝癌介入术后感染性并发症的独立危险因素。控制改善这些危险因素有助于预防减少介入术后感染性并发症的发生。“,”Objective To explore the relevant risk factors of infectious complications after transhepatic arterial chemotherapy and embolization (TACE) in primary hepatic carcinoma. Methods From January to December in 2014,730 medical records diagnosed as primary hepatic carcinoma and applied with TACE intervention in our hospital were collected.The univariate analysis was used to analyze 21 possible factors related with infectious complications after intervention.Factors that were displayed statistical significances after univariate analysis were analyzed the correlation between these factors and infectious complications after surgery in hepatic carcinoma by non-conditional binary multi-ple Logistic regression analysis. Results Forty-one cases occurred with infectious complications after interventions in these 730 cases,the incidence of postoperative infectious complications was 5.62%.Univariate analysis indicated that risk factors of infectious complications occurred after surgery included combinations of chronic bronchitis,low albumin level,ascites,ectopic embolization,and partial splenic embolization before surgery (P<0.05).Multiple Logistic regression analysis showed combinations of chronic bronchitis,low albumin level,ascites,ectopic embolization,and partial splenic embolization were independent risk factors of infectious complications after interventional operation (P<0.05). Con-clusion Combinations of chronic bronchitis,low albumin level,ascites,ectopic embolization and partial splenic emboliza-tion simultaneously are independent risk factors of infectious complications after interventional operation. To control and improve these risk factors is beneficial to prevent and reduce the occurrence of infectious complications.