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目的 探讨部分脾栓塞治疗小儿血液病的临床疗效、免疫功能及并发症。方法 采用 Seldinger` s法 ,行部分脾栓塞 (Partial Splenic Embolization,PSE)治疗小儿慢性特发性血小板减少性紫癜 (Idiopathic Thrombocytopenic Purpura,ITP)、先天性红细胞丙酮酸激酶缺陷症及脾功能亢进共 13例 ,选用明胶海绵颗粒作为栓塞剂 ,栓塞范围控制在 6 0 %～ 80 %之间。结果 患儿在术后 2周血小板升至正常 ,临床症状改善 ,栓塞前后免疫球蛋白无明显变化 ,无严重并发症。结论 PSE治疗部分小儿血液病例可保留小儿的免疫功能 ,取得满意疗效 ,值得临床推广。
Objective To investigate the clinical efficacy, immune function and complications of partial splenic embolization in the treatment of pediatric hematological diseases. Methods Seldinger’s method and Partial Splenic Embolization (PSE) were used to treat Idiopathic Thrombocytopenic Purpura (ITP), pyruvate kinase deficiency of congenital erythrocytes and hypersplenism Example, the use of gelatin sponge particles as embolic agents, embolism range between 60% to 80%. Results In 2 weeks after operation, children’s platelets rose to normal and their clinical symptoms improved. There was no significant change in immunoglobulin before and after embolization without serious complications. Conclusion PSE treatment of some cases of pediatric blood can retain the immune function in children, and achieved satisfactory results, worthy of clinical promotion.