初生乳鼠自出生当天起皮下注射谷氨酸钠2mg/g,连续5天,可复制成小鼠肥胖模型,表现为至6周龄后可发生进行性肥胖。自4周龄断乳后(即肥胖发生前)开始灌喂花粉5～10g/kg,连续30天,对小鼠肥胖有明显的预防作用。花粉预防组的体重和肥胖指数(Lee’s Index)明显低于不用花粉的致肥组,并能显著降低血清和肝脏胆固醇与甘油三酯及体内脂肪含量。本文结果提示花粉可能有益于肥胖症的预防,值得临床试用。 The primary neonatal mice were injected subcutaneously with sodium glutamate 2 mg/g from the day they were born and for 5 consecutive days, they were able to replicate into a mouse model of obesity, which showed that progressive obesity may occur after 6 weeks of age. After 4 weeks of age weaning (ie, before obesity) began to feed pollen 5 ~ 10g/kg, continuous 30 days, has a significant role in the prevention of obesity in mice. The pollen prevention group’s body weight and obesity index (Lee’s Index) were significantly lower than those without pollen, and significantly reduced serum and liver cholesterol, triglycerides, and body fat content. This article suggests that pollen may be beneficial for the prevention of obesity and is worthy of clinical trials.