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目的 :观察青霉素、硫酸庆大霉素对红剑鱼、孔雀鱼和食蚊鱼的急性毒性影响 ,以探讨红剑鱼、孔雀鱼和食蚊鱼作为水生实验动物的可行性及对药物急性毒性的检测效果。方法 :用水毒理学方法测定它们对三种鱼类的 2 4hLC50 。结果 :青霉素对红剑鱼、孔雀鱼和食蚊鱼的急性毒性观察结果 ,2 4hLC50 值分别为 2 83.0 6mg/L、2 79.92mg/L、2 89.4 4mg/L ;硫酸庆大霉素对红剑鱼、孔雀鱼和食蚊鱼的急性毒性观察结果 ,2 4hLC50 值分别为 2 95 .97ug/L、2 73.74ug/L、30 9.0 3ug/L。结论 :红剑鱼、孔雀鱼和食蚊鱼可作为急性毒性的试验材料。
Objective: To investigate the acute toxicity of penicillin and gentamicin sulfate to red swordfish, guppy and mosquito fish in order to investigate the feasibility of using red swordfish, guppy and mosquito fish as aquatic experimental animals and acute toxicity test effect. METHODS: Water toxicology was used to determine their 24 h LC50 for three species of fish. Results: The acute toxicities of penicillin to red swordfish, guppies and mosquitoes showed that the 24 h LC50 values were 2 83.0 6 mg / L, 2 79.92 mg / L and 2 89.4 4 mg / L, respectively. The acute toxicity of fish, guppies and mosquitoes showed that the values of 24hLC50 were 2 95.97ug / L, 2 73.74ug / L and 30 9.0 3ug / L, respectively. Conclusion: Red sword fish, guppies and mosquito fish can be used as acute toxicity test material.