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目的:分析西宁地区充血性心力衰竭(CHF)一氧化氮(NO)的含量变化及其临床意义。方法:检测59例临床确诊为CHF的患者血浆NO含量,另选31例健康体检者作为正常对照组。结果:西宁地区CHF患者血浆NO水平明显高于对照组(P<0.01),且心衰程度越重,NO水平越高。结论:血浆NO可作为反映CHF严重程度的客观指标之一,且在CHF病理生理改变中起重要作用。
Objective: To analyze the changes of nitric oxide (NO) in patients with congestive heart failure (CHF) in Xining and its clinical significance. Methods: Plasma NO levels were measured in 59 patients with clinically diagnosed CHF, and 31 healthy controls were selected as normal control group. Results: The NO level in plasma of CHF patients in Xining was significantly higher than that of the control group (P <0.01). The more serious heart failure was, the higher the NO level was. Conclusion: Plasma NO can be one of the objective indicators reflecting the severity of CHF, and plays an important role in the pathophysiology of CHF.