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目的研究对高血压伴心力衰竭患者实施美托洛尔强心治疗后患者的心功能改善情况。方法选择2013年9月至2015年2月高血压伴心力衰竭患者98例,将患者随机分为研究组和对照组。对照组用苯磺酸氨氯地平片治疗,研究组用美托洛尔治疗,分别治疗6个月共2个疗程,测量两组患者治疗后的心率、血压、左室舒张期末内径(LVDd)、左室射血分数(LVEF)指标情况并判断两组患者治疗后的效果。结果研究组治疗后心率(66±9)次/min,舒张压(72.32±1.70)mm Hg(1 mm Hg=0.133 k Pa),收缩压(108.45±2.30)mm Hg,LVDd(48.40±1.30)mm,LVEF(67.40±1.20)%;对照组治疗后心率(82±8)次/min,舒张压(78.32±2.10)mm Hg,收缩压(78.32±2.10)mm Hg,LVDd(60.74±1.20)mm,LVEF(61.40±1.50)%,两组比较差异均有统计学意义(P<0.05)。研究组总有效率为95.91%,明显高于对照组(79.59%),差异有统计学意义(χ~2=6.0775,P=0.0137)。结论实施美托洛尔强心治疗后,高血压伴心力衰竭患者心功能情况改善较为明显,值得临床推广应用。
Objective To study the improvement of cardiac function in patients with hypertension complicated with heart failure after metoprolol cardiac treatment. Methods From September 2013 to February 2015, 98 patients with hypertension and heart failure were randomly divided into study group and control group. The control group was treated with amlodipine besylate, and the study group was treated with metoprolol. The patients in the study group were given 2 courses of treatment for 6 months respectively. The heart rate, blood pressure, end-diastolic diameter (LVDd) , Left ventricular ejection fraction (LVEF) indicators and determine the effect of two groups of patients after treatment. Results After treatment, heart rate (66 ± 9) / min, diastolic pressure (72.32 ± 1.70) mm Hg (1 mm Hg = 0.133 k Pa), systolic blood pressure (108.45 ± 2.30) mm Hg and LVDd (48.40 ± 1.30) (78.32 ± 2.10) mm Hg, systolic pressure (78.32 ± 2.10) mm Hg, LVDd (60.74 ± 1.20) mmHg, LVEF (67.40 ± 1.20) mm and LVEF (61.40 ± 1.50)%, respectively, with significant difference between the two groups (P <0.05). The total effective rate of the study group was 95.91%, which was significantly higher than that of the control group (79.59%), the difference was statistically significant (χ ~ 2 = 6.0775, P = 0.0137). Conclusion After the implementation of metoprolol cardiac therapy, heart failure in patients with hypertension and heart failure to improve the situation is more obvious, it is worthy of clinical application.