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1987年6月～1989年6月,经皮经腔激光辅助血管成形术50例病人。男43例,女7例,年龄中位数64岁。48例间歇性跛行,2例休息时足疼痛及局部缺血性溃疡。病人无凝血病、新近脑溢血或出血性溃疡病史。症状持续时间中位数12月,闭塞长度中位数8 cm(1～21cm)。92%病人膝以下可见到2或3条开放动脉。多普勒踝-臂收缩压力指数(AAI)休息时(AAIr)中位数0.6(0.0～0.9),运动后指数(AAIe)中位数0.3(0.0～0.8),步行距离(W D)中位数300m(10～890m)。术前抗凝治疗持续时间中位数1月。术前1天阿斯匹林600mg+心痛定10mg,4次/日。术中动脉内肝素10000IU,静脉低分子右旋糖酐100ml/h。术后双香豆素治疗1月,阿斯匹林600mg/日连续治疗1年。局麻下7 F导管鞘顺行插入股总动脉。激光导管:外面为7 F导管、内有一根直径0.6mm二氧化
From June 1987 to June 1989, 50 patients underwent percutaneous transluminal laser-assisted angioplasty. There were 43 males and 7 females, with a median age of 64 years. 48 cases of intermittent claudication, 2 cases of rest pain and ischemic ulcer. Patient has no history of coagulopathy, recent stroke or hemorrhagic ulcer. The median duration of symptoms was 12 months, and the median occlusion length was 8 cm (1 to 21 cm). Two or three open arteries were seen below the knee in 92% of patients. Median 0.6 (0.0-0.9), AAIe median 0.3 (0.0-0.8), median walking distance (WD) were significantly higher at AAI resting (AAI) and Doppler ankle-arm systolic pressure index Number of 300m (10 ~ 890m). Preoperative anticoagulant therapy median duration of January. One day before surgery aspirin 600mg + nifedipine 10mg, 4 times / day. Intraoperative arterial heparin 10000IU, intravenous low molecular weight dextran 100ml / h. Postoperative coumarin treatment in January, aspirin 600mg / day for 1 year. Local anesthesia with 7 F catheter sheath inserted into the common femoral artery. Laser catheter: external 7 F catheter, which has a diameter of 0.6mm dioxide