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异名 ImIGran,GR43175C 化学名 3-[2-(二甲胺基)乙基]-N-甲基-1 H-吲哚-5-甲胺基磺酰基丁二酸药效分类抗偏头痛药开发单位 (英国)Glaxo LaboratoriesLtd 上市厂商 1991年在荷兰首次上市偏头痛是一种单侧型头痛,常伴有恶心和呕吐。在西方国家有10％以上的人患有此病,且大多数患者为女性。其病因学机制尚待阐明,但已知偏头痛与颅血管显著而持续的扩张有关。偏头痛一直是用麦角胺来治疗的,该药对颈动脉吻合具有血管收缩作用,
Synonym ImIGran, GR43175C Chemical Name 3- [2- (dimethylamino) ethyl] -N-methyl-1H-indole-5-methylaminosulfonyl succinic acid Pharmacodynamic class Anti-migraine medicine Developer (UK) Listed Glaxo Laboratories Ltd Listed in Netherlands for the first time in 1991 Migraine is a unilateral headache, often accompanied by nausea and vomiting. More than 10% of people in the West suffer from the disease, and most are women. Its etiology is yet to be elucidated, but migraine is known to be associated with a significant and sustained dilation of cranial blood vessels. Migraine has been treated with ergotamine, which has a vasoconstrictive effect on carotid anastomosis,