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目的:确定维生素B1片理想的溶出度测定方法。方法:采用紫外-可见分光光度法。结果:维生素B1片在盐酸溶液(9→1000)中溶出度效果较为理想。结论:该方法简单、准确,可作为维生素B1片的体外溶出试验方法。
OBJECTIVE: To determine the ideal method for determination of dissolution of vitamin B1 tablets. Methods: UV-visible spectrophotometry. Results: The dissolution rate of vitamin B1 tablets in hydrochloric acid solution (9 → 1000) is more satisfactory. Conclusion: This method is simple and accurate and can be used as in vitro dissolution test of vitamin B1 tablets.