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目的分析影响１５３ＳｍＥＤＴＭＰ对肿瘤转移性骨痛治疗效果的相关因素。方法对我院近两年使用１５３ＳｍＥＤＴＭＰ行内照射治疗的５９例肿瘤转移性骨痛病人进行回顾性分析，按年龄、病灶数量、不同肿瘤分组，单次剂量给予１５３ＳｍＥＤＴＭＰ１８．５～３７ＭＢｑ／ｋｇ静脉注射，第２天行全身骨显像观查放射分布情况，建立随访。结果总有效率为９３．６％。在年龄组中，以老年组效果最好，止痛有效率为９６．９％；病灶数量组以多发灶效果最好，有效率为９５．７％；不同肿瘤组以乳腺癌、鼻咽癌、前列腺癌效果好，有效率为１００％。结论静脉注射１５３ＳｍＥＤＴＭＰ对肿瘤转移性骨痛内照射治疗是一种良好的治疗方法，疗效肯定。其止痛效果受病人的年龄、骨转移程度和肿瘤组织类型等因素的影响
Objective To analyze the related factors affecting the therapeutic effect of 153Sm-EDTMP on metastatic bone pain. Methods A retrospective analysis of 59 patients with metastatic bone pain in our hospital who had been treated with 153Sm-EDTMP in our hospital for the past two years was performed. According to age, number of lesions, and different tumors, a single dose was given to 153Sm-EDTMP 18.5 to 37 MBq/. Intravenous injection of kg, on the second day, whole body bone imaging was performed to observe the radiological distribution, and a follow-up was established. The total effective rate was 93.6%. In the age group, the old group had the best effect, the effective rate of analgesia was 96.9%; the number of lesions group had the best effect with multiple lesions, the effective rate was 95.7%; different tumor groups were breast cancer, nasopharyngeal carcinoma, The effect of prostate cancer is good, and the effective rate is 100%. Conclusions Intravenous injection of 153Sm-EDTMP is a good treatment for internal metastases of bone metastases. The curative effect is certain. The analgesic effect is influenced by the age of the patient, the degree of bone metastasis, and the type of tumor tissue.