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目的探讨化疗联合放疗应用于中晚期宫颈癌患者的有效性和安全性。方法 85例中晚期宫颈癌患者,采用放疗治疗对照组42例患者,化疗联合放疗治疗观察组43例患者,对比两种治疗方案对中晚期宫颈癌患者的影响。结果对患者进行随访,观察组1年的存率高达97.67%,3年的生存率达到93.02%,5年的生存率达到88.37%。对照组1年的生存率达到88.10%,3年的生存率达到80.95%。5年的生存率仅仅达到59.52%。观察组的生存率显著高于对照组,差异具有统计学意义(P<0.05)。对照组的不良反应较多,不良反应发生率高达57.14%。观察组的不良反应较少,不良反应发生率24.91%,差异具有统计学意义(P<0.05)。结论化疗联合放疗应用于中晚期宫颈癌患者的有效性较高,大大提高了患者的生存率,值得推荐。
Objective To investigate the efficacy and safety of chemotherapy combined with radiotherapy in patients with advanced cervical cancer. Methods Totally 85 patients with advanced cervical cancer were treated with radiotherapy in 42 patients in the control group and 43 patients in the radiotherapy combined with radiotherapy group. The effects of the two treatment regimens on patients with advanced cervical cancer were compared. Results The patients were followed up. The survival rate of the observation group was 97.67% at 1 year, 93.2% at 3 years, and 88.37% at 5 years. The 1-year survival rate of the control group reached 88.10%, 3-year survival rate reached 80.95%. 5-year survival rate of only 59.52%. The survival rate of the observation group was significantly higher than that of the control group, the difference was statistically significant (P <0.05). The adverse reaction in the control group was more, the incidence of adverse reactions was as high as 57.14%. Adverse reactions in the observation group was less, the incidence of adverse reactions was 24.91%, the difference was statistically significant (P <0.05). Conclusion The combination of chemotherapy and radiotherapy in patients with advanced cervical cancer is more effective and greatly improves the survival rate of patients, it is recommended.