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众所周知,血吸虫病药物实验的疗效波动很大。Bell(1965)比较了各作者用Stibocaptate治疗曼氏血吸虫病患者的疗效,发现治愈率波动范围为20—100%。硝唑咪的疗效也相仿,特别是曼氏血吸虫病地区,虽然该药对埃及血吸虫病的疗效向来波动较小和良好。造成这些差异最重要的因素,可能是作者们所采用的寄生虫学检查方法不同和治愈标准各异。为了比较试验,不能忽视这类基本因素的标准化。注意到16年前Newsome(1
As we all know, the efficacy of schistosomiasis drug experiment fluctuations. Bell (1965) compared the efficacy of stibocaptate to treat Schistosoma mansoni and found that the cure rate ranged from 20% to 100%. The efficacy of nifedipine is similar, especially in the area of Schistosoma mansoni, although the drug’s effects on echinococcosis in Egypt have shown little to no change. Perhaps the most important contributing factor to these differences is the different methods of parasitology used by the authors and the different standards of cure. In order to compare experiments, we can not ignore the standardization of such basic factors. Noted Newsome (16 years ago)