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目的探讨头孢类药物引发不良反应的原因与对策。方法选取50例出现头孢类药物不良反应患者,设为观察组;150例同期用药未出现不良反应患者设为对照组,回顾性分析2组临床资料,统计观察组引发不良反应的头孢类药物种类不良反应类型及原因及对照组非头孢类药物引发的不良反应,并进行比较。结果引发不良反应的头孢类药物以3代头孢类药物为主;患者存在过敏体质、有过敏史和用药后饮酒等均为引发不良反应高风险因素。结论使用头孢类药物需明确用药指征,严密监控患者用药过程,积极建立不良反应防范应对措施。
Objective To investigate the causes and countermeasures of cephalosporins induced adverse reactions. Methods Fifty patients with adverse reactions of cephalosporins were selected as the observation group. One hundred and fifty patients with no adverse reactions during the same period of treatment were enrolled as the control group. The clinical data of two groups were retrospectively analyzed. The types of cephalosporins The types and causes of adverse reactions and adverse reactions caused by non-cephalosporins in the control group were compared and compared. Results The main adverse reactions caused by cephalosporins 3 generation cephalosporins; patients with allergies, allergies and alcohol consumption after treatment are high risk factors for adverse reactions. Conclusion The use of cephalosporins drugs need to be clear indications for the use of drugs, close monitoring of patient medication, and actively establish adverse reactions to prevent countermeasures.