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目的探讨血吸虫病肝纤维化的家庭聚集性。方法在洞庭湖血吸虫病重度流行区,用便携式B超检查261户939例渔民肝实质纤维化分级情况。采用Poisson分布优度拟合与负二项分布优度拟合相结合进行统计分析。结果洞庭湖重度流行区渔民血吸虫病的肝纤维化程度分布超出了Poisson分布范围(P<0.05),而且与负二项分布重合,有明显的家庭聚集性(P>0.05)。结论血吸虫病肝纤维化程度分布有明显家庭聚集性。
Objective To investigate the familial aggregation of schistosomiasis with hepatic fibrosis. Methods In the endemic area of schistosomiasis endemic to Dongting Lake, the grading of hepatic parenchymal fibrosis in 939 fishermen from 261 households was examined by portable B-mode ultrasonography. The poisson distribution goodness-of-fit and negative binomial distribution goodness-of-fit were combined for statistical analysis. Results The distribution of liver fibrosis in fishery schistosomiasis in the endemic areas of Dongting Lake exceeded the Poisson distribution range (P <0.05), and coincided with the negative binomial distribution, with significant family aggregation (P> 0.05). Conclusion schistosomiasis degree of liver fibrosis with obvious family aggregation.