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目的:探讨两种不同呼吸机通气模式对慢性阻塞性肺疾病伴呼吸衰竭患者血气、呼吸功能的影响及并发症出现情况。方法:分析2012年1月~2014年12月在我院接受治疗的85例COPD合并呼吸衰竭患者的临床资料,观察组(41例)患者采用适用性支持通气模式(ASV),对照组(44例)患者联合采用压力支持通气模式(PSV)和同步间歇指令通气模式(SIMV)。结果:两组研究对象在HR、呼吸频率、MAP、PH、Sp O2、Pa O2、Pa CO2及P(A-a)O2指标水平比较上,差异均无统计学意义;观察组患者MRV明显高于对照组,观察组患者VT低于对照组;观察组患者吸气流量高于对照组。观察组患者呼吸比、气道闭合压明显低于对照组;观察组患者并发症发生率明显低于对照组。结论:相比SIMV+PSV模式,ASV通气模式可以维持COPD伴呼衰患者自主呼吸功能,减少呼吸肌做功,并发症较少,具有一定的临床指导意义。
Objective: To investigate the effects of two different ventilator ventilation modes on the blood gas and respiratory function in patients with chronic obstructive pulmonary disease and respiratory failure and the occurrence of complications. Methods: The clinical data of 85 COPD patients with respiratory failure who were treated in our hospital from January 2012 to December 2014 were analyzed. The patients in the observation group (41 cases) received ASV and control group 44 Example) Patient combination pressure support ventilation (PSV) and synchronized intermittent mandatory ventilation (SIMV). Results: There was no significant difference in HR, respiration rate, MAP, PH, Sp O2, Pa O2, Pa CO2 and P (Aa) O2 between the two groups. MRV in the observation group was significantly higher than that in the control group VT in observation group was lower than that in control group. Inspiratory flow in observation group was higher than that in control group. The respiratory rate and airway closure pressure in the observation group were significantly lower than those in the control group. The complication rate in the observation group was significantly lower than that in the control group. CONCLUSIONS: Compared with SIMV + PSV model, ASV ventilation mode can maintain spontaneous respiratory function in COPD patients with respiratory failure and reduce the work of respiratory muscles with less complications, which is of clinical significance.